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  1. The New England Journal of Medicine | Research & Review Articles on ...

    The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles, and editorial opinion on a wide variety of topics of ...

  2. Bleeding Risk with Apixaban vs. Rivaroxaban in Acute Venous ...

    Mar 11, 2026 · Apixaban and rivaroxaban are the oral anticoagulants most frequently used to treat acute venous thromboembolism. However, uncertainty remains about the difference in bleeding risk …

  3. Romiplostim versus Placebo for Chemotherapy-Induced …

    Mar 11, 2026 · Chemotherapy-induced thrombocytopenia (CIT) is a common complication of chemotherapy that is associated with bleeding, reduced relative dose intensity, and potentially worse …

  4. Perioperative Enfortumab Vedotin and Pembrolizumab in Bladder Cancer

    Feb 18, 2026 · Patients with muscle-invasive bladder cancer who are ineligible for cisplatin-based chemotherapy proceed directly to radical cystectomy with pelvic lymph-node dissection. …

  5. Recently Published | The New England Journal of Medicine

    1 day ago · Explore this issue of The New England Journal of Medicine (Vol. 0 No. 0).

  6. Teclistamab plus Daratumumab in Relapsed or Refractory Multiple …

    Dec 9, 2025 · In a phase 1–2 trial, teclistamab, a bispecific antibody targeting CD3 on T-cell surfaces and B-cell maturation antigen on myeloma cells, showed durable responses in heavily pretreated …

  7. Medical Management and Revascularization for Asymptomatic Carotid ...

    Nov 21, 2025 · Improvements in medical therapy, carotid-artery stenting, and carotid endarterectomy call into question the preferred management of asymptomatic carotid stenosis. Whether adding …

  8. One Pivotal Trial, the New Default Option for FDA Approval — Ending …

    Feb 18, 2026 · This Sounding Board announces a new FDA policy that the default requirement for FDA approvals will be one robust pivotal trial plus confirmatory evidence, rather than two trials.

  9. A Placebo-Controlled Trial of the Oral PCSK9 Inhibitor Enlicitide

    Feb 4, 2026 · Enlicitide decanoate, an oral proprotein convertase subtilisin–kexin type 9 (PCSK9) inhibitor, was shown to reduce low-density lipoprotein (LDL) cholesterol levels in a phase 2 trial; …

  10. Discontinuation of Beta-Blocker Therapy after Myocardial Infarction ...

    6 days ago · The role of long-term beta-blocker therapy after a myocardial infarction in patients without left ventricular systolic dysfunction or heart failure is unclear in the era of contemporary coronary-ar...