The crystal structure of bacteriophage T7 RNA polymerase complexed to a DNA promoter is the first high resolution structure of an open promoter complex. The orientation of the bound template and the ...

In Biology 101, we learn that RNA is a single, ribbon-like strand of base pairs that is copied from our DNA and then read like a recipe to build a protein. But there's more to the story. Some RNA ...

The process starts with a “primer”, a short fragment of RNA (or DNA) that matches a strand of RNA (or DNA). In order to make a new strand from the existing strand, the primer needs to be extended. To ...

RNA produced within cells of a common budding yeast can serve as a template for repairing the most devastating DNA damage – a break in both strands of a DNA helix, scientists have found. The ability ...

Suggested Citation: "1 Introduction." National Academies of Sciences, Engineering, and Medicine. 2024. Charting a Future for Sequencing RNA and Its Modifications: A New Era for Biology and Medicine.