Most people think of Alzheimer’s disease as an illness of aging. But in fact, the brain changes that characterize it begin much earlier – sometime around the third decade of life. In the earliest of ...

The locus coeruleus is a region of the brain that is instrumental in coordinating our mental processing and is the primary source of noradrenaline in the brain, which acts to regulate arousal states ...

The earlier it's detected, the earlier treatment can start.

Tau aggregation begins not in the cortex, but in the brainstem. Does tangle deposition in the locus coeruleus, which often starts in a person’s 30s, presage Alzheimer’s disease? In the September 22 ...

Tsukuba, Japan—Mild exercise results in a feeling of mental clarity and enhances cognition and memory. A possible mechanism behind such effects is the activation of the arousal center in the brainstem ...

Losing your sense of smell might signal Alzheimer’s far earlier than expected. Scientists found that immune cells in the brain actively destroy smell-related nerve fibers after detecting abnormal ...

Engaging the brain’s plasticity by stimulating the locus coeruleus, a region in the brainstem, could be a clinically relevant approach to optimize the efficacy of cochlear implants in restoring ...

Turns out, your brain isn’t just a squishy mass of pinkish-grey. Hidden deep inside is a tiny “blue spot” that plays a major role in our cognition — and a new study shows that it goes through a ...

Andrew Luskin conducted research on the brain's peri-locus coeruleus neurons while he was a UW Medicine neuroscience Ph.D. student. A small cluster of cells deep within our brains, called the locus ...

Norepinephrine-producing neurons in the locus coeruleus, a small nucleus in the brainstem, have been discovered to have two distinct types of cells that connect linearly via gap junctions -- novel ...

Small and seemingly specialized, the brain's locus coeruleus (LC) region has been stereotyped for its outsized export of the arousal-stimulating neuromodulator norepinephrine. In a new paper and with ...