Bioengineers have developed a platform that accurately replicates conditions cancer cells encounter while traveling through the bloodstream.

Metastasis, the spread of cancer from a primary tumor to other parts of the body, is difficult to study in the lab, in part ...

Traditionally, scientists have used 2D cell cultures as in vitro models in drug screening studies due to their simplicity and scalability. However, 2D cell models do not recapitulate the complexity of ...

This article is based on a poster originally authored by D. Cole and N. Bevan. 3D models, including spheroids and organoids, are increasingly used to investigate disease and development. Developing, ...

Most potential oncology drugs fail during the drug development pipeline, even when there has been promising data for their efficacy during the in vitro stage. This makes it vital to identify in vitro ...

New confocal fluorescence imaging minimizes photobleaching and phototoxicity effects, capturing clear images of live 3D culture Industry-leading throughput enables real-time analysis of up to six ...

A simulated cell in the early stages of division. Left half shows membrane (green cubes), and ribosomes (yellow/purple) ...

D models coupled with live-cell imaging can enhance the overall reliability of preclinical renal safety evaluations.

Growing cells in three dimensions is critical for studying how tissues behave in the body, yet most laboratory platforms remain either too simple or too complex to use widely. Researchers now present ...